β-migrating very-low-density lipoprotein, chylomicron remnants and their receptors
نویسندگان
چکیده
منابع مشابه
Very-low density lipoprotein metabolism.
This manuscript was presented in part at the 31st Annual Meeting of the Council on Arteriosclerosis, American Society for the Study of Arteriosclerosis, American Heart Association. 1977. Circulation. 56(Suppl. III): 22. (Abstr.) Received for publication 2 December 1977 and in revised form 9 February 1978. and apoC) contained by negative staining, many disklike structures. The study demonstrated...
متن کاملVery Low Density Lipoprotein (VLDL)
Triglyceride (TG) or more accurately triacylglycerol is simply a compound of three acyl groups (fatty acids) attached to a glycerol molecule. They are easily measured in the laboratory and reported as serum TG level: it actually refers to all of the TG that are being trafficked within all of the lipoproteins that exist in a deciliter of plasma. A physiologic fasting TG concentration is on avera...
متن کاملRole of low density lipoprotein receptor-dependent and -independent sites in binding and uptake of chylomicron remnants in rat liver.
The role of the low density lipoprotein (LDL) receptor in the binding of chylomicron remnants to liver membranes and in their uptake by hepatocytes was assessed using a monospecific polyclonal antibody to the LDL receptor of the rat liver. The anti-LDL receptor antibody inhibited the binding and uptake of chylomicron remnants and LDL by the poorly differentiated rat hepatoma cell HTC 7288C as c...
متن کاملEndocytosis of very low density lipoprotein remnants by liver of fasted rats.
Radioactive lipoproteins in the very low density lipoprotein (VLDL) density range were taken up by rat liver in vivo. The radioactivity became associated with an intracellular particle of d = 1.11 that did not correspond to lysosomes, endoplasmic reticulum, or plasma membrane as determined by marker enzyme distribution. Radioactive VLDL remnants could be released from these particles by passage...
متن کاملRabbit beta-migrating very low density lipoprotein increases endothelial macromolecular transport without altering electrical resistance.
Rabbit aortic endothelial cells (RAEC) were grown on micropore filters in a new device. This system allowed in situ measurement of transendothelial electrical resistance (TEER). The monolayers demonstrated a TEER of 14 +/- 1 omega X cm2 at confluence. No difference was seen in the transport of low density lipoproteins (LDL) across endothelial cell monolayers obtained from normal or Watanabe her...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1995
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj3100359a